As a reminder, I called this in 2004.

that sound you hear is me pressing X to doubt

Yud in the replies:

The essence of valid futurism is to only make easy calls, not hard ones. It ends up sounding prescient because most can't make the easy calls either.

"I am so Alpha that the rest of you do not even qualify as Epsilon-Minus Semi-Morons"

i suspect - i don't know, but suspect - that it's really leveraging all known protein structures ingested by google and it's cribbing bits from what is known, like alphafold does to a degree. i'm not sure how similar are these proteins to something else, or if known interacting proteins have been sequences and/or have had their xrds taken, or if there are many antibodies with known sequences that alphaproteo can crib from, but some of these target proteins have these. actual biologist would have to weigh in. i understand that they make up to 96 candidate proteins, then they test it, but most of the time less and sometimes down to a few, which suggests there are some constraints. (yes this counts as one iteration, they're just taking low tens to 96 shots at it.) is google running out of compute? also, they're using real life xrd structures of target proteins, which means that 1. they're not using alphafold to get these initial target structures, and 2. this is a mildly serious limitation for any new target. and yeah if you're wondering there are antibodies against that one failed target, and more than one, and not only just as research tools but as approved pharmaceuticals