All of the above depending on what your budget is.

Many software emulations are more than serviceable, and again depending on your budget can offer some really advanced parameter controls to mimic different types of speakers in differently sized cabinets being recorded with different types of mics in different recording spaces.

Pedals can still vary widely in quality, but there are some really good ones out there that can serve as a backup in case there's any on-stage technical problems, or even serve as a completely fine fly rig in and of themselves.

Kemper makes the top of the line stuff these days (so far as I know, it's been a couple years since I payed very close attention to cutting edge tech). Their profiling amps allow you to make complete profiles of real amps and cabs through recording a series of signals through that rig. These profiles can be shared online and downloaded straight onto their "heads" which can be rack mounted in a studio setup. For stage use they have versions that serve as a typical amplifier head would, or use the form factor of those multi-effect floor units. They sound incredible.