As a general suggestion, tones people (me for sure included) sculpt when playing by themselves tend to make things sound muddy when playing with other instruments due to overlapping frequencies. To combat this, dial back the highs and especially the lows. It'll sound kind of thin on its own, but that's what the other instruments are for.

A good way to figure out how to come up with your own tones is to pick a few presets in one of the Neural Archetypes that you really like and a few that you don't like. Try to find the commonalities between them. Just as examples, maybe the ones you like have a lot of gain or highs and maybe the ones you don't all have a flanger on them.

A "good" sound is entirely subjective and dependent on the genre you're playing. Can you give some examples of sounds you're trying to create?