I've used MO2.
However, I have to say that the most-convenient way I've used with Bethesda games, if you're going to start with a modlist from Wabbajack, is to use Jackify.
https://github.com/Omni-guides/Jackify
It'll set up MO2, create a new, modded Steam entry for the modlist (so, like, it won't fiddle with your vanilla game install), pull down and set up the associated mods in the correct order, and you can fiddle with said modlist in MO2 after installation.
If what you want is "game with modern updates and then maybe a few particular custom changes that I want", I'd say that that is easily the most painless route in 2026.