Air blower, Q-Tip, Toothpick? And Isopropanol is the cleaning fluid of choice for electronics. I've also used my vacuum on Thinkpads before. But beware the vacuum. If anything is just tucked in, it'll dislodge it and suck it in. And you get to spend the next 20min trying to find some tiny part in a pile of dust and hairballs.
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Also the plastic parts of the vacuum cleaner tend to build up static change when rubbed, so be careful not to zap your electronics.
And avoid fans, spin them fast and they're generators, with a good chance of reverse polarity to the intended. In fact, judicious canned air is probably better than a vacuum, but you use what you've got, it's a thinkpad, it'll probably be fine.
+1 to Isopropanol, (unused) makeup brushes can also be useful.
Yes. Thx, I forgot about that. Especially the insides. You probably want to have a look inside, if the outside already looks that dirty. And the case / outside is probably fine with some light zapping. It went through ESD testing and certification. And should be able to deal with electrostatic discharge in some way. But the (individual) components on the inside are way more delicate and not made to withstand it.
Compressed air to start with. Rubbing alcohol and an old toothbrush for what remains after that.
