It would hold it more firmly to your mouth membranes instead of being flipped around, so yeah I guess? But is it even perceptual? Not sure, never tried.
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That is a very good question.
I'm sure it'd have some effect, since the pressure differential would dilate the capillaries under the tongue, but I've got no idea how much of an effect that'd have.
No.
No, it's a marketing gimmick. Think about how fast oxygen gets to your cells, that's how fast anything get's around your blood. If a medication take's a while to kick in it's usually because another process needs to happen first, like Tylenol and your liver. The only tiny bit of truth to it is that thin membranes do absorb better, like your stomach, mouth, and butthole.