I don’t know of any by name or have proof they exist, but I feel like there are recreational drugs that enhance sensations. I don’t think they’d beat anesthesia though.
I do feel like there is some kind of drug like that that would be used in “interrogation” though. So the way Ibuprofen, that you named, works is, it reduces inflammation that can cause pain. Then you have acetaminophen (Tylenol) which reduces the signals pain receptors send to the brain. You still feel the pain, but your brain ignores some of it. It logically follows that the opposite effect is also possible, but I am not aware of a drug that actually does that that you can buy (I am also unaware of any you can’t buy, to be clear).