this post was submitted on 31 Mar 2025
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Explain Like I'm Five

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[–] cattywampas@lemm.ee 7 points 3 days ago (1 children)

CTE has no distinct biomarkers and doesn't involve any structural damage that's visible to any of our current imaging capabilities.

[–] Cort@lemmy.world 3 points 3 days ago (1 children)

How is it diagnosed post mortem? Does a human being have to pull the brain out and look through a magnifying glass?

[–] floo@retrolemmy.com 2 points 2 days ago

In short, yes. Of course, they have to dissect the brain first.

[–] jeffw@lemmy.world 4 points 3 days ago

We can’t see Alzheimer’s either

[–] slazer2au@lemmy.world 2 points 3 days ago (1 children)
[–] Vanth@reddthat.com 7 points 3 days ago* (last edited 3 days ago)

Chronic traumatic encephalopathy.

It's a summation of low grade damage over years and years from activities like football, rugby, hockey. Physical evidence requires an autopsy or maybe tracking changes in the brain over years (which no NFL player watching out for his paycheck is going to want to do).

That's not to say there won't be a way to detect it in still-live people in the future. CTE is still "new" in the context of medicine, which moves at glacial paces.