Almost every skill provides new dialog skill checks ranging from merely funny to altering your options for quest resolution.

As you progress in new or other skills, you reveal new parts of quests that every BGS and similar game before would require new games for.

The set pieces for the Main Quest and Factions are rife with alternate paths and options to also make use of new skills.

The Ryujin one for example, I'm up to 6 runs and still enjoying variating. Mind control guy to hack computer and blow up door? Which of the three vents is best, the one that requires Gymnastics and space magic? The one behind the security computer?

Alternate "timelines" switching up the Main Quest/replacing it entirely.

A system emulating the idea of endless possibilities for a discrete purpose; You can easily add more of all of this to the mix with as much or as little fanfare as you want, and it'll fit right in.

I for one, hope individual devs start getting lee way to remix quest lines the same way they were allowed to do new environmental stories for future DLCs like they did for Skyrim's DLC tenure.

I can keep going. Seriously. There's plenty of game and innovation alongside the rest of what makes a human released software product a jank mess of an attempt to deny the Universe's entropic march.

Just gotta be willing to trade a smirk for a smile for a lot of people reading this.