Cuba's Interior Ministry has announced that four men on a US-registered speedboat were shot and killed after being intercepted in Cuban waters.

When a Cuban boat carrying five members of the ministry's border guard approached the vessel for identification, "the crew of the violating speedboat opened fire" and wounded the Cuban commander, the statement said.

"As a consequence of the confrontation, as of the time of this report, four aggressors on the foreign vessel were killed and six injured," the statement added.

Those injured were evacuated and given medical assistance.