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Taking acetaminophen during pregnancy does not increase risk of autism, ADHD or intellectual disabilities (medicalxpress.com)

submitted 3 days ago* (last edited 3 days ago) by schizoidman@lemmy.zip to c/science@lemmy.world

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Taking acetaminophen during pregnancy does not increase the risk of autism, attention-deficit hyperactivity disorder (ADHD), or intellectual disability among children. That is according to the most rigorous analysis of the evidence to date, published in The Lancet Obstetrics, Gynecology & Women's Health, and led by researchers from City St George's, University of London.

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[+] U7826391786239@lemmy.zip -10 points 3 days ago* (last edited 3 days ago) (1 children)

have they done studies on what it's doing to the fetus's liver and kidneys?

edit: lol nevermind, i guess

[–] deliriousdreams@fedia.io -2 points 3 days ago (1 children)

    Hinchliffe SA, Sargent PH, Howard CV, Chan YF, van Velzen D. Human intrauterine renal growth expressed in absolute number of glomeruli assessed by the disector method and Cavalieri principle. Lab Invest. 1991;64:777-784.
    Hartman HA, Lai HL, Patterson LT. Cessation of renal morphogenesis in mice. Dev Biol. 2007;310:379-387.
    Brenner BM, Chertow GM. Congenital oligonephropathy and the etiology of adult hypertension and progressive renal injury. Am J Kidney Dis. 1994;23:171-175.
    Brenner BM, Garcia DL, Anderson S. Glomeruli and blood pressure. Less of one, more the other? Am J Hypertens. 1988;1:335-347.
    Guignard JP. Nephron deficit: causes and late consequences. Arch Pediatr. 2005;12:726-727.

Edit: https://pubmed.ncbi.nlm.nih.gov/34105801/

[–] TheTechnician27@lemmy.world 10 points 3 days ago* (last edited 3 days ago) (1 children)

Uhhh... Just as a quick spot check, Brenner & Chertow (1994) doesn't mention acetaminophen/paracetamol even a single time (checked the full paper). Did you use an LLM to generate this list?

It's arguably silly to answer this kind of transparent firehose of falsehoods whose believers don't care about medical science by scrambling to put together lists debunking them, but if you're going to do that, at least do it right.

[–] deliriousdreams@fedia.io 3 points 3 days ago (1 children)

This list is a source list from one of the articles I looked up. I have never used an LLM for literally anything in my life.

https://pubmed.ncbi.nlm.nih.gov/34105801/

[–] TheTechnician27@lemmy.world 3 points 3 days ago

Okay, that at least clears some things up. I haven't checked the other four papers you listed, to be clear, but Brenner & Chertow (1994) isn't even about analgesics generically. I'm perplexed that you didn't just link to the abstract for Penna et al. (2021) to begin with, especially because it doesn't seem like you've read any of these or the paper you got them from. That's why I assumed an LLM: because even reading just reading the title of Brenner & Chertow (1994), you can tell it's only tangentially relevant to what's being discussed.