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Large-scale study confirms that millions of people are taking a heart attack drug unnecessarily
(english.elpais.com)
this post was submitted on 18 Nov 2025
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how is 18,000 underpowered.
Power is a function of the size of the difference you're testing for. Idk how to really calculate it accurately, but this site would suggest to discriminate between 7.2% and 7.4% you'd need over 300,000 participants
I'm kind of skeptical of that, but I don't know enough about clinical trials to know that.
8,400 were assigned