this post was submitted on 20 May 2025
687 points (99.3% liked)
Privacy
43207 readers
998 users here now
A place to discuss privacy and freedom in the digital world.
Privacy has become a very important issue in modern society, with companies and governments constantly abusing their power, more and more people are waking up to the importance of digital privacy.
In this community everyone is welcome to post links and discuss topics related to privacy.
Some Rules
- Posting a link to a website containing tracking isn't great, if contents of the website are behind a paywall maybe copy them into the post
- Don't promote proprietary software
- Try to keep things on topic
- If you have a question, please try searching for previous discussions, maybe it has already been answered
- Reposts are fine, but should have at least a couple of weeks in between so that the post can reach a new audience
- Be nice :)
Related communities
much thanks to @gary_host_laptop for the logo design :)
founded 6 years ago
MODERATORS
you are viewing a single comment's thread
view the rest of the comments
view the rest of the comments
The 99.9% similarity refers to humans having nearly identical DNA sequences, but that doesn’t mean we express our genes the same way. Gene expression varies widely due to regulatory sequences, environmental factors, epigenetics, methylation, and more.
23andMe only analyzes a small, curated set of common SNPs, covering maybe 5 - 10 percent of the known functional and trait-associated genome. It doesn’t sequence most rare variants, the full exome, or structural elements.
Recent research is also starting to highlight the growing importance of the dark genome, revealing that non-coding regions we’ve dismissed as junk DNA play significant roles in regulation and disease.