My $0.02c worth - I have run all sorts of servers at home over the years, and one of the main challenges around the hardware is managing heat.

I’ve used mini-ITX mobos and tiny cases for builds. They look gorgeous, but at some point, when you stick enough drives in there (assuming you can) or make the CPU/GPU busy, you are going to have a heat problem, or a noise problem, or both.

On my mythtv build I used M-itx and a gorgeous Lian Li small case. It was a beautiful add to my home theatre stack, but in the end I drilled a ton of small holes in the top and added a slow 140mm fan to control the heat without noise.

The same goes for my file server - it was a slightly larger case with no GPU, but once I added my 6th HDD and had a ton of services running, heat became an issue and I was having to add extra fans, which could only be 80mm so they ran fast and noisy.

My new build I’m going to go all the way with a Phanteks Enthoo Full Tower and a few 120mm fans. I’ve decided that looks don’t matter

The other problem for me with these tiny builds is cable management. I’m complete shit at it, and small builds requires some skills. A big case gives you space to spread those cables out.

Lastly, you can get ATX or EATX mobos with 6, 8 or more SATA connectors - room for growth! And there are very low power options available.

I’ll soon have the appleTV + TV upstairs, laptop in the office, and the monster server downstairs with cat-6 + Gb fibre throughout.