rah

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30
An 80-year-old woman with late-stage Alzheimer's took 5g of psilocybin mushrooms, slept for 19 hours, woke up and started speaking again (www.microdos.in)
 

A new case report published in Frontiers in Neuroscience describes an extraordinary but highly preliminary observation: an 80-year-old woman with advanced Alzheimer's disease showed temporary multidomain improvement after receiving a high dose of psilocybin-containing mushrooms.

Following administration of 5g of mushrooms, she entered a prolonged deep sleep-like state. After waking, she reportedly regained the ability to speak in full sentences, recognised family members, dressed independently, and recovered urinary continence after five years.

A later 3g dose appeared to extend some of these improvements.

11
A psychedelic surprise: DMT helps the brain heal after stroke (www.sciencedaily.com)
Today is the third anniversary of the Coronation of His Majesty, Our dear and noble King Charles III, and Her Majesty, our gracious Queen Camilla! in c/unitedkingdom@feddit.uk
[–] rah@feddit.uk 4 points 2 months ago (1 children)

10
She tried therapy and medication, but this grandmother says psilocybin is what changed her life | CNN (edition.cnn.com)
Single dose of potent psychedelic drug could help treat depression, trial shows in c/warondrugs@feddit.uk
14
Single dose of potent psychedelic drug could help treat depression, trial shows (www.theguardian.com)
 

A small clinical trial involving 34 people found that psychedelic-assisted therapy prompted a swift reduction in depressive symptoms that endured long after the drug had worn off, with some still feeling the benefits six months later.

Although preliminary, the results add to a growing body of evidence that psychedelic drugs, when coupled with psychotherapy, could help to alleviate depression in the millions of people worldwide who do not respond to existing antidepressants or therapies.

The trial, reported in Nature Medicine, focused on people with moderate to severe treatment-resistant depression. One half received a single 21.5mg dose of DMT infused into a vein over 10 minutes. The other half received a placebo infused the same way. All of the participants had psychotherapy and follow-up assessments.

Patients given DMT improved significantly compared with the placebo group, as measured by scores on a standard depression questionnaire, with the antidepressant effects lasting from three to six months.

In the second stage of the trial, all participants received a dose of DMT with therapy, but the researchers found no additional benefit in those who had two doses in total, suggesting a single dose may suffice. The trial was designed, funded and sponsored by Cybin UK, a neuropsychiatric firm.

The study follows a positive trial with psilocybin, the active ingredient in magic mushrooms, which has raised hopes for the drug being approved for treatment of depression later this year.

At doses used in the trials, DMT induces a shorter but more intense trip than psilocybin, with the experience lasting about 25 minutes compared with a couple of hours for psilocybin. That could make DMT-assisted therapy easier for clinics to deliver, although patients may need more support to recover from particularly intense DMT trips.

If regulators were to approve psychedelics for treating depression in the UK, researchers expect them to become available only through private clinics, said Dr James Rucker, a consultant psychiatrist at King’s College London who worked on the psilocybin trial.

Last year the Feilding commission was set up to guide the safe, ethical and equitable rollout of psychedelic-assisted therapies amid concerns that commercial pressures at private clinics could undermine safety, leading to patient harm.

Rucker said: “Quite how these drugs will fit in this world of financial austerity, stigma and opprobrium towards anything that has the word psychoactive in it, I don’t know. It’s interesting to be a part of, but I can’t call it.”

13
Zack Polanski Has Pledged to Legalise Drugs. So Should All Leftwing Leaders (novaramedia.com)
What is this flashlight? in c/flashlight@lemmy.world
[–] rah@feddit.uk 6 points 8 months ago

What is this flashlight?

It is black.

7
Green leader Zack Polanski backs legalisation of all drugs (www.bbc.com)
11
‘Who wouldn’t want pure cocaine?’: the radical plan to prevent overdoses with better drugs (www.theguardian.com)
 

The big bag of meth will get weighed out into individual doses and put into tiny cardboard boxes, labeled with its contents, purity, and the logo of Dulf – the Drug User Liberation Front.

The office’s location is not on any maps or findable by any search engines, but it is not exactly secret. Vancouver’s government, the cops, drug users and maybe even dealers all know where it is, and it turns out that has been pretty much fine, despite the fact that the people inside it are buying and selling felony-level quantities of drugs every week.

Such is life in Vancouver, where the drug problem has been so bad for so long that the authorities here have, reluctantly and with a lot of pressure, begun to allow for a kind of radical experimentation not really going on anywhere else.

She envisions a future in which heroin and every other drug are handled similarly to alcohol: regulated, free from impurities, legal and available to the public. She does not see any other way out of the crisis. Everything else people have tried has simply not worked.

Non-paywalled: https://archive.is/JpdEO

I need an antidepressant that does NOT make you tired all the time. in c/publichealth@mander.xyz
[–] rah@feddit.uk 2 points 11 months ago

I am back on Lexapro

Guanfacine which I take

I take Abilify as well

I take Vyvanse too

I need to pinpoint why I am so tired all the time...

Can't imagine why...

Transphobia guidelines in c/feddituk@feddit.uk
[–] rah@feddit.uk 0 points 1 year ago* (last edited 1 year ago) (1 children)

A conservative forum is a forum run by conservatives for conservatives and limits itself to conservative positions

Says who?! It can mean whatever you define it to mean. You're just making stuff up, you're no authority.

It’s a general purpose discussion forum that can touch on topics like conservativism, socialism or biking.

This is not the way you presented feddit.uk before. You seemed to be explicitly excluding conservativism.

I’m not going to list all the things this place is not as that’s an infinity long list.

Of course but I would point out that social conservativism is the dominant political philosophy in the UK so it would be odd and in fact misleading not to be up front about excluding conservativism in an instance that advertises itself as a general UK instance. Hence my concern.

Polite bigotry is still bigotry, do you think we should allow race realists if they mind their Ps and Qs correctly?

Most definitely. How else could such views be shown up for what they are using sound reason and subtle but devastating wit, as is the British way? (As opposed to sticking one's fingers in one's ears and shouting "LA LA LA LA LA I CAN'T HEAR YOU UR DUMB I'MA BAN U".)

even tolerant Britain doesn’t let them inject these believes wherever, social spaces like pubs and community events still limit what can take place in them.

I'm not sure what you're trying to say with this but I would note that with one exception, all the racist people I've had the misfortune of encountering have been in pubs. And moreover, I wouldn't want to spend time in any pub where any kinds of 'certain' discussions were outright prohibited.

https://www.youtube.com/watch?v=7jssqYTMf9E

I don’t see why we should be more accepting of transphobia

Debating isn't the same thing as accepting.

The only things these guidelines ask you to do is not promote fear or hatred of trans people and that you aren’t allowed to say that a trans person’s gender identity is less valid than a cis person’s.

It seems you've changed your tune:

1. In response to the question "The instance is never an appropriate context and any such discussion whatsoever is prohibited?": "Yes, ..."

2. "It’s about protecting a vulnerable minority. ... I don’t want this place to be a contributor to these statistics and I’m going to prioritise the safety of our trans users over some notion of neutrality."

And also, to be clear:

3. In response to the question "if someone created a linguistic philosophy community on feddit.uk and in that community members held a discussion on ‘a trans person’s “I’m a man” as less than a cis person’s “I’m a man”’, is that prohibited or not?" which is about discussion of whether a trans person's “I’m a man” is less than a cis person’s “I’m a man” and doesn't necessarily imply saying anything one way or the other: "no [yes] as that’s pretty clearly ..."

I wonder what reasonable ‘philosophical discussion’ this excludes

There's plenty. Wouldn't it be great if we created a place where such wonderings could be explored honestly without concern over being banned? What a pity that instead there's a place of dullness, with rules motivated by fear.

Transphobia guidelines in c/feddituk@feddit.uk
[–] rah@feddit.uk 1 points 1 year ago* (last edited 1 year ago) (3 children)

This not being a conservative forum isn’t the same as conservatives not being welcome, I believe we even have some around.

This is irrelevant to the issue at hand. Whatever it is that feddit.uk is not, please state that up front in the "Who are we?" section. If feddit.uk is not a conservative forum, please state "feddit.uk is not a conservative forum" in the "Who are we?" section. That would at least give people more clarity on what feddit.uk is, who is here and what they can expect when they post from here.

This is getting very tiresome for what is a very little ask

By the same token, clarifying what feddit.uk is and is not in the "Who are we?" section seems to me like a very little ask.

don’t be transphobic. This has been a rule on the site literally from inception.

But the new "guidelines" and more importantly the statements from an admin (yourself) in comments under this post about what feddit.uk is not, are all new. As far as I know, philisophical discussion of trans issues had never been prohibited before.

My understanding of feddit.uk until this post was that it would reflect general wider social mores of British society: tolerance, even of those who have what we feel to be reprehensible views, up to the point where it's clear a person is uncivil or unreasonable. Now my understanding of feddit.uk is different: there are some areas of discussion which are not tolerated under any circumstances, regardless civility or reasonableness. There is now an ideological component, not to the makeup of the user population (which has always been obvious), but to the governance of the instance which is a whole different kettle of fish and very new. Now, feddit.uk has an official ideological position: not a conservative forum, social discussion, no philosophical debate about trans issues, etc.

Transphobia guidelines in c/feddituk@feddit.uk
[–] rah@feddit.uk 1 points 1 year ago* (last edited 1 year ago) (5 children)

This is pretty categorically not a conservative forum

This comment along with others like

This is a social discussion forum not a linguist philosophy one

and

That wouldn’t really change the fact this is a place for discussion of things with other people.

make it clear that feddit.uk has an agenda: it's for lefty social discussion.

Adding @tom@feddit.uk @Emperor@feddit.uk

Can I suggest making that agenda clear in the "Who are we?" section of feddit.uk 's front page so that people are aware of what they're signing up for and that this isn't just a general UK instance? In particular, it seems egregious to me that there is no mention of the fact that conservatives aren't welcome.

What's the worst case of enshitification you've seen lately? in c/askuk@feddit.uk
[–] rah@feddit.uk 2 points 1 year ago* (last edited 1 year ago)

Christ I just saw that you're OP. I'm confused; why did you use the word "enshittification" if you didn't know what it meant?

What's the worst case of enshitification you've seen lately? in c/askuk@feddit.uk
What's the worst case of enshitification you've seen lately? in c/askuk@feddit.uk
[–] rah@feddit.uk 0 points 1 year ago (3 children)

it arguably comes under the umbrella or enshitification

How so?

"first, they are good to their users; then they abuse their users to make things better for their business customers; finally, they abuse those business customers to claw back all the value for themselves. Then, they die. I call this enshittification" -- https://en.wikipedia.org/wiki/Enshittification

Complex Systems Won’t Survive the Competence Crisis in c/collapse@lemm.ee
What's the worst case of enshitification you've seen lately? in c/askuk@feddit.uk
[–] rah@feddit.uk 0 points 1 year ago (5 children)

That's not enshitification?

26
POV: You're a Russian HGV driver and you just pulled over for a snack (feddit.uk)
submitted 1 year ago* (last edited 1 year ago) by rah@feddit.uk to c/ukraine@sopuli.xyz
1 comments fedilink
 

h/t https://9gag.com/gag/avyvmzd

48
Deal with EU will make food cheaper and add £9bn to UK economy, says No 10 (www.theguardian.com)
 

The deal – which will grant EU fishers access to British waters for an additional 12 years – will remove checks on a significant number of food products as well as a deeper defence partnership and agreements on carbon taxes.

The UK said the deal would make “food cheaper, slash red tape, open up access to the EU market”. But the trade-off for the deal was fishing access and rights for an additional 12 years – more than the UK had offered – which is likely to lead to cries of betrayal from the industry.

The two sides will also begin talks for a “youth experience scheme”, first reported in the Guardian, which could allow young people to work and travel freely in Europe again and mirror existing schemes the UK has with countries such as Australia and New Zealand.

The government said it would put £360m of modernisation support back into coastal communities as part of the deal, a tacit acknowledgment of the concession.

31
Drought conditions already hitting UK crop production, farmers say (www.theguardian.com)
19
Medical cannabis shows potential to fight cancer, largest-ever study finds (www.theguardian.com)
 

The largest ever study investigating medical cannabis as a treatment for cancer, published this week in Frontiers in Oncology, found overwhelming scientific support for cannabis’s potential to treat cancer symptoms and potentially fight the course of the disease itself.

15
Whistleblowers warn UK food industry heading for climate disaster (www.thegrocer.co.uk)
 

cross-posted from: https://slrpnk.net/post/20676198

cross-posted from: https://lemmy.nz/post/21414090

The memo, shared with The Grocer, warns food businesses are woefully unprepared for challenges including soil degradation, extreme weather events, global heating and water scarcity and that yield, quality and predictability of food supply are all at severe risk.

It goes on to claim that companies’ risk mitigation strategies are being assured by major audit and assurance firms and giving false confidence to investors, whereas the true threat to the supply chain is far greater than companies have acknowledged.

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