Hot pixels! Best way to deal with them is taking dark frames: a bunch of exposures with the exact same settings as your light/main frames, but with the lens cap on so it just captures the noise. Also important that your camera is roughly the same temperature as when you took the light frames, since this type of noise is very temperature dependent. Once you have your dark frames, you can stack them to make a master dark, and use this to subtract the hot pixels from your lights using a deep sky stacking program of your choice.
Side note: for most consumer cameras, using a higher ISO will actually lower noise, at the cost of dynamic range