Depends on your needs and goals. Traditional art etc Krita is solid. Runs everywhere. Windows Mac Linux Android and iOS. There are some more focused on pixel art like pixieditor. And still more focused on vector art like inkscape.
Digital Art

Community rules:
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Be respectful and considerate in comments.
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No deliberately offensive or inappropriate content.
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Traditional artists and posts are also welcome here.
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All posts must properly credit the original artist.
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Please use the tickbox to mark any NSFW content.
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No A.I. generated dreamscapes for now, as those are at best unethically sourced in the current state.
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No furry or anthro related art.
How to post:
Please follow the convention of the images already uploaded so far i.e.:
Image title by Artists Name
In the description link the source to the image, and also include a direct link to the artists gallery. See previous posts for examples.
What to post:
You can post your own work here, but avoid spamming.
You can post your favourite peices here for us all to enjoy.
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All artworks are copyright of the artists named in the posts.
Artists gallery links may contain NSFW works.
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Thank you!
Blender also has grease pencil, and pressure sensitive pen support for their sculpting tools if I recall correctly.
Ah yeah, I've dabbled in Blender before. Good idea!
3D:
- Blender
2D:
- Paint.NET
- Krita
- GIMP
Vector graphics:
- inkscape (garbage user interface but it works)
- Blender (convert grease pencil into curves then export SVGs)
Thank you for your thorough response!
Ya welcome. Also, if you want better vector software than Inkscape but not expensive like Adobe look into "Affinity Designer"
It's basically the same as illustrator with a few key differences but also has an iPad app too.
As someone who spent obscene amounts of time growing up on/learning photoshop, Krita is pretty much the closest. In terms of workflow for photography, non-destructive editing, etc. it only takes very minor tweaks to adjust but otherwise feels native. There’s also tons of resources for it.
I’ve heard good things about Inkscape in terms of vector graphics, but haven’t used it yet myself.
Worst case scenario you try out a program and move on, and since it’s free there’s very little pressure.
Good luck!
Thanks!