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Just a reminder: These massive drives are really more a "budget" version of a proper tape backup system. The fundamental physics of a spinning disc mean that these aren't a good solution for rapid seeking of specific sectors to read and write and so forth.
So a decent choice for the big machine you backup all your VMs to in a corporate environment. Not a great solution for all the anime you totally legally obtained on Yahoo.
Not sure if the general advice has changed, but you are still looking for a sweet spot in the 8-12 TB range for a home NAS where you expect to regularly access and update a large number of small files rather than a few massive ones.