The instance seems to be mostly right wing trolls. I know defederating is unpopular but I don't think much is to be lost in this case and it can save the mods some headaches.
Edit: the response on exploding-heads.com to my reporting of transphobia. Courtesy of the "second in command"
Radicalisation starts with people "just asking questions" or "just pointing out an issue with X without having anything against them", that's enough to hook some people that will go way down the rabbit hole.
In the screenshot you see exactly what I'm talking about, "I'm not racist, but I can point out issues with the BLM movement". Alright they just opened the door to people that are a bit more radical to try and find out where the tolerance ends and to others to start looking for answers with a biased premise in mind.
I invite you to watch this video (and the whole series really) that covers all of that:
https://youtu.be/P55t6eryY3g