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Ultrasound can push vaccines into the body without needles
(www.newscientist.com)
This is a most excellent place for technology news and articles.
Miniatyrize ultrasound part, make it communicare with those glucose sensors that are placed on shoulder, make it portable enough and Presto! Artificial pancreas.
Nice Idea!
Even the long application time is no issue there, since you just carry the device with you