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This is a difficult thing to accurately assess. While we can use spectrometry to find chemical compositions of stars and nebulae and planet atmospheres/surfaces, we cant even be certain about the interior of planets and moons within our own solar system, much less the galaxy.
We can make educated guesses based on the mass/volume and the stability of elements but I don't think it’s an exact science.
However, i would imagine the answer to your question is No, the galaxy is not homogeneous. My reasoning is that near the center of our galaxy, stars are much closer together. This not only makes stellar collisions more likely to occur, but also means there will be significantly more cosmic rays in that space than out here near the rim.
Both cosmic rays and stellar collisions are the (theoretical) primary sources of certain elements. Berylium and Boron are created by cosmic rays fission, and as such id expect their concentrations to be higher in denser star clusters. And I’d expect higher concentrations of heavier elements due to both increased collisions AND due to the decay chains of unstable isotopes created by cosmic ray fission.
Cosmic rays are responsible for producing common isotopes like Carbon-14 here on earth, and we live in a pretty empty part of space near a relatively inactive star. So I’d imagine the amount of radioactive isotopes of all kinds would generally be higher in more dense stellar regions too.
All that being said, the most common elements will probably be the same. Hydrogen and helium are the most common in the entire universe, and many light elements like Oxygen and Carbon and even Iron which can be produced by fusion will probably be higher in concentration than any heavier elements regardless of where you are in the universe.