this post was submitted on 09 Mar 2026
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Thrombosis is generally used for the formation of a blood clot (thrombus) in a vein. However, not all thrombi are formed inside veins, as in the case of cardiac thrombi.
Embolism is when a thrombus dislodges from its place and occludes a blood vessel somewhere else. If it originates from a vein it usually ends up in the lung vasculature – pulmonary embolism.
Cardiac embolism usually ends up in the brain – ischaemic stroke.
A plaque is a build-up of atheroma (gunk) on the wall of an artery. If that happens in the carotid artery part of that plaque may dislodge and end up in the brain, causing ischaemic stroke.
Ischaemic strokes are very rarely caused by embolism of thrombosis (thrombo-embolism from the veins), in which case it is often referred to as a paradoxical embolism.