Rebooting is a good idea from time to time to ensure any new updates have taken fully and that old system drivers haven't lasted and continued to run.

For example, one time I installed an XOrg update but didn't reboot because my distro's updater didn't recommend it. And so I was very confused when I actually did reboot and graphics were borked. It took me a while to track down that the update - which I'd forgotten about - hadn't been compatible with my graphics driver and I'd been using the previous working version until then.

It's supposedly possible to restart / reload all software without rebooting, but it's a royal pain in the [proverbial] when it's deep in the system, and it's far easier to just reboot.

And if you're gonna reboot anyway, you could time that nicely for before you'd be about to stop using the computer for a while. Let it reboot first to make sure everything seems OK with any updates that might have been applied. When that works, you're at a fresh slate with no programs open, so you can then turn it off.

(And if it hasn't worked, you can roll back with something like Timeshift or whatever your distro provides, check that works and save the investigation for when you have time.)