this post was submitted on 04 Jan 2026
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Anti-Aging Injection Regrows Knee Cartilage and Prevents Arthritis (scitechdaily.com)
submitted 4 months ago by Lemmar@lemmy.today to c/science@lemmy.world
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In mice (of course) and human tissue exvivo. Earlier phase 1 studies with 15-PGDH has shown that it is safe and active in healthy volunteers.

Reference: “Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration” by Mamta Singla, Yu Xin Wang, Elena Monti, Yudhishtar Bedi, Pranay Agarwal, Shiqi Su, Sara Ancel, Maiko Hermsmeier, Nitya Devisetti, Akshay Pandey, Mohsen Afshar Bakooshli, Adelaida R. Palla, Stuart Goodman, Helen M Blau and Nidhi Bhutani, 27 November 2025, Science. DOI: 10.1126/science.adx6649

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[–] Lemmyoutofhere@lemmy.ca 54 points 4 months ago (17 children)

As a 50+ year old mechanic, this can’t come soon enough.

[–] roofuskit@lemmy.world 12 points 4 months ago (6 children)

Perfect for making you work the remainder of your life. No more arthritis? Great, now work until death to pay for it.

[–] angrystego@lemmy.world 2 points 4 months ago

I don't think arthritis is the win you think it is.

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