this post was submitted on 04 Jan 2026
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ADHD

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Does anyone else experience variation in what the effect of their meds feels like?

I've gradually increased my dose to 2 x 30 mg of slow release methylphenidat and have had a couple of days where I felt fantastic. Very focused but also calm and balanced. I had this very strong feeling of "really being myself" as in being able to use my full potential as a person.

Then I have some days where I barely notice anything and today I've mostly just felt jittery and a bit anxious. I can feel the stimulating effect on my body (higher heart rate) but without the mentally calming effect.

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[–] timmytbt@sh.itjust.works 2 points 3 months ago

My wife has noticed that “Long acting” can build up in her system, leading to those jittery symptoms. Make sure you’re drinking enough water to flush things through. She’ll often change to short acting for a day or two once a fortnight to ensure she’s getting rid of it all.