Probably not, I can't inmediately notice it, but you see, games like Ez2On Reboot: R have a very robust customization suite, including timing adjustment and indicators for when you press a key too early or too late. The game combines both features on a single option where you play a song while the game automatically adjusts the delay between your keystrokes and the "target" you're supposed to be hitting. Using that feature, the game added around 3ms window to my keystrokes, and after a couple of game sessions, you can actually feel the game being slightly off-beat (since those kind of games actually play sounds whenever you press a key, your "play" sounds slightly delayed using the rest of the song being auto played by the PC). Also, the early/late counter at the end of each song increases one way or another. Again, it's not immediately noticeable, but you feel something's off and the results screen can confirm it.